Objective: A more sustainable use of resources in terms of the diagnosis and management of emerging zoonotic diseases, reducing them substantially while increasing the cost effectiveness of extensive livestock, hunting and hunting farms.

Evolution: It has been possible to apply efficient and cheaper methods that reduce potential losses (number of slaughtered animals, movement restrictions,..) in livestock and hunting farms. By having a better diagnosis, as well as faster, it is achieved that, those farms based on the territory such as hunting farms (where native game species are raised with health guarantee), hunting farms (that manage territories of the natural environment ) and extensive livestock, are more sustainable. In addition, the improvement of the health status of the animals that this project contributes has an impact on a safer food chain.

This project has been supported with financial aid from the government of Castilla La Mancha and the European Union through the European Regional Development Fund.

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Tuber salud animal

ESTUGA, sponges for environmental diagnosis of animal tuberculosis

Objective: The objective of the ESTUGA project is to test and validate this new environmental DNA detection system for mycobacteria causing TB in field conditions so that it can be used to certify the absence of tuberculosis in farms.


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The red chicken mite, Dermanyssus gallinae (red chicken mite), is an ectoparasite that is considered the worst pest in the laying poultry sector. It feeds in the dark on the blood of chickens, but it can also affect humans both in their workplace and in public buildings. It produces serious economic losses and affects the health and well-being of the hens, as well as being vectors of diseases. The mite has developed resistance to commonly used pesticides so other control measures are necessary.

Through molecular techniques, mite proteins have been identified that can be used as vaccines. The development of vaccines is a very promising option by not developing resistance and reducing the use of pesticides in the environment.

The ACAROVAC project works for the development of vaccine candidates against infestations by Dermanyssus gallinae (red chicken mite).

This project was born under the Aid for Industrial Doctorates of the Ministry of Economy and Competitiveness through the State Program for the Promotion of Talent and its Employability of the State Plan for Scientific and Technical Research and Innovation, with financing for recruitment for training of doctors in companies.

Ministerio de Ciencia e Innovación

The contracted researcher, Jose Francisco Lima Barbero, after defending his doctoral thesis, already carries his doctorate from the UCLM, with the congratulations of the entire Sabiotec team for their efforts, which can be seen in the following presentations and articles:

Objective: the aim is to develop new reproductive control methodologies, applicable to deer and small ruminant hunting farms to improve their production and sustainability, minimizing reproductive seasonality and obtaining value-added dairy products.

Results: the final product allows the delivery of certain active ingredients for oral intake, effective to seasonally adjust reproduction and increase animal production. In addition, it will allow to obtain an enriched dairy product with the consequent benefit for human health.


Dehesa de los Llanos LS

Medianilla LS

Marantona AS

Group SaBio: University of Castilla la Mancha

Project Subsidized by CDTI and FEDER

Union Europea Feder


Control of tuberculosis in animals through vaccines and multi-species diagnoses


The overall objective of the WILDTBVac project is to take the results of the TB-STEP project - Strategies for the eradication of bovine tuberculosis, funded under FP7-KBBE-2007 with project number 212414, where most of the WildTBVac partners were involved, and build a pre-commercial set of TB control solutions by means of testing the technical and economical viability of the aforementioned integrated approach.

Recent studies have showed estimations of worldwide 50 million cattle infections with Mycobacterium bovis, at a cost to the agricultural community of 2-3 billion € per year. In developing countries, M. bovis infection is still widespread, in both cattle and humans. Even in developed countries, successful eradication of disease from livestock is hampered by the presence of wildlife reservoirs of M. bovis. Under these circumstances, a single case of a reportable disease in livestock can result in serious economic consequences for the producer, public, and governments. Within this scenario, there is room and clear business opportunities for integrated control products or solutions that aim at addressing what is considered a global problem, animal tuberculosis.

The objectives of the WILDTBVac project are:

1. To standardise and optimise the production of a vaccine against TB (prototype result from the TB-STEP project)
2. To evaluate various diagnostic strategies compatible with vaccination (also the result of the TB-STEP project) that will include multi-species DIVA (differentiating infection in vaccinated animals) tests (swine, cattle).
3. To evaluate the efficiency in the field of integrated TB control strategies, including the oral vaccination to control TB in wild boar.
4. To evaluate the efficiency in the field of integrated TB control strategies, including the oral vaccination to control TB in domestic and wild pigs.
5. To define the operational and marketing strategy, including guidelines for technology transfer and the development of market-oriented business. Sabiotec is involved in this objective.

WILDTBVac project is funded under FP7-KBBE-2013-613799